Python Interview Questions – Industry Expert Level (25 Q&A)

Architecture, Performance, Debugging, CI/CD, Automation & Production-grade Python.

1️⃣ How do you design a scalable Python application architecture?
class PaymentService:
  def __init__(self, gateway):
    self.gateway = gateway

  def pay(self, amount):
    return self.gateway.process(amount)
pip install fastapi uvicorn
2️⃣ How do you handle memory leaks in long-running Python services?
import tracemalloc
tracemalloc.start()
python memory_test.py
3️⃣ Multithreading vs Multiprocessing – how do you design?
from multiprocessing import Pool
Pool(4).map(pow, [1,2,3,4], [2,2,2,2])
4️⃣ How do you debug Python slowdown in production?
python -m cProfile app.py
5️⃣ How do you design Python REST APIs for enterprise scale?
@app.get("/health")
async def health():
  return {"status": "UP"}
uvicorn main:app --reload
6️⃣ How do you automate Python tests in CI/CD?
pytest --maxfail=1 --disable-warnings
7️⃣ How do you troubleshoot Python dependency conflicts?
pip freeze > requirements.txt
8️⃣ Exception chaining for root cause analysis?
try:
  int("abc")
except ValueError as e:
  raise RuntimeError("Parsing failed") from e
9️⃣ Retry & exponential backoff design?
import time
for i in range(3):
  try:
    call_api()
    break
  except:
    time.sleep(2**i)
🔟 How do you optimize Python DB performance?
pip install sqlalchemy
11️⃣ Debug Python deadlocks?
Analyze thread dumps, avoid nested locks, use timeouts.
12️⃣ Python automation framework design?
POM, reusable utilities, data-driven tests.
13️⃣ Large file processing?
for line in open("big.log"):
  process(line)
14️⃣ Python app security?
export API_KEY=xyz
15️⃣ Profile memory vs CPU?
python -m memory_profiler app.py
16️⃣ Package import errors?
which python
17️⃣ Event-driven Python systems?
pip install kafka-python
18️⃣ Log correlation?
logging.info("req_id=%s", rid)
19️⃣ Unicode issues?
open("file.txt", encoding="utf-8")
20️⃣ Optimize startup time?
python -X importtime app.py
21️⃣ API testing without UI?
curl http://localhost:8000/health
22️⃣ Plugin architecture?
import importlib
23️⃣ Graceful shutdown?
signal.signal(signal.SIGTERM, handler)
24️⃣ Debug hanging process?
kill -SIGUSR1 <pid>
25️⃣ Production-ready Python checklist?
✔ Logging ✔ Monitoring ✔ Testing ✔ CI/CD ✔ Containers
docker build -t python-app .
🌙